Search results for "Energy methods"
showing 4 items of 4 documents
Molecular basis of SARS-CoV-2 infection and rational design of potential antiviral agents: Modeling and simulation approaches
2020
International audience; The emergence in late 2019 of the coronavirus SARS-CoV-2 has resulted in the breakthrough of the COVID-19 pandemic that is presently affecting a growing number of countries. The development of the pandemic has also prompted an unprecedented effort of the scientific community to understand the molecular bases of the virus infection and to propose rational drug design strategies able to alleviate the serious COVID-19 morbidity. In this context, a strong synergy between the structural biophysics and molecular modeling and simulation communities has emerged, resolving at the atomistic level the crucial protein apparatus of the virus and revealing the dynamic aspects of k…
A dissipated energy comparison to evaluate fatigue resistance using 2PB
2012
Flexural fatigue due to repeated traffic loading is a process of cumulative damage and one of the main failure modes of flexible pavement structures. Typically, micro-cracks originate at the bottom of an asphalt concrete layer due to horizontal tensile strains. Micro-cracking starts to propagate towards the upper layers under repeated loading which can lead to pavement failure. Different approaches are usually used to characterise fatigue resistance in asphalt mixtures including the phenomenological approach, the fracture mechanics approach and the dissipated energy approach. This paper presents a comparison of fatigue resistance calculated for different dissipated energy models using 2 Poi…
On relation between J-integral and heat energy dissipation at the crack tip in stainless steel specimens
2019
In this paper, an experimental procedure to evaluate the elastic-plastic J-integral at the tip of a fatigue crack is presented. According to this new approach, the elastic component of the J-integral is derived from Thermoelastic Stress Analysis, while the plastic component of the J-integral is derived from the heat energy loss. An analytical link is proposed to apply this new experimental technique. Therefore, the elastic-plastic J-integral range was evaluated starting from infrared temperature maps measured in situ during crack propagation tests of AISI 304L stainless steel specimens. It was found that the range of the infrared thermography-based J-integral correlated well the crack growt…
Infrared thermography-based evaluation of the elastic-plastic J-integral to correlate fatigue crack growth data of a stainless steel
2019
Abstract The elastic-plastic J-integral is adopted to correlate fatigue crack growth data of ductile metals. An analytical link is known to exist between the J-integral and the strain energy density averaged in a control volume embracing the crack tip. On the other hand, the strain energy fluctuation is the source of temperature variations close to a fatigue crack tip of a metal material; hence the possibility to measure the J-integral from infrared thermographic scanning at the crack tip is envisaged and it is the focus of this paper. It is proposed that the elastic component of the J-integral is derived from a thermoelastic stress analysis, while the plastic component of the J-integral is…